There are literally hundreds of motonoeuron dieseases (MND), all of which can be classified according to whether they iinherited or sporadic, and whether the upper motor neurons, lower motor neurons, or both are affected during the course of the disease. The most common MND is amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

Among the more common other MNDs are:

  • Progressive bulbar palsy, also called progressive bulbar atrophy
  • Post-polio syndrome (PPS)
  • Pseudobulbar palsy
  • Primary lateral sclerosis (PLS)
  • Progressive muscular atrophy

Spinal muscular atrophy (SMA) subtypes include:

  • SMA type I (Werdnig-Hoffmann disease)
  • Symptoms of SMA type II SMA type III (Kugelberg-Welander disease)
  • Congenital SMA with arthrogryposis
  • Kennedy’s disease, also known as progressive spinobulbar muscular atrophy

Comprehensive English-language information about the broad spectrum of motorneuron diseases, including fact sheets, can be found here: National Institute of Neurological Disorders and Stroke

Comprehensive German-language information can be sought here: German Motoneuron Disease Society (DGM)

Funding